International Review of Ophthalmology

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Recent developments in prognostic factors for uveal melanoma

YAN Yan-ni, WEI Wen-bin.   

  1. Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology ＆ Visual Sciences Key Lab., Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
  • Received:2016-07-18 Online:2016-10-22 Published:2016-10-25
  • Contact: WEI Wen-bin, Email: weiwenbintr@163.com
  • Supported by:

    Beijing Municipal Administration of Hospitals’Ascent Plan (DFL20150201); Science & Technology Project of Beijing Municipal Science & Technology Commission (Z151100001615052); National Natural Science Foundation of China (81570891); Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support (ZYLX201307) ; Beijing Natural Science Foundation (7151003); Advanced Health Care Professionals Development Project of Beijing Municipal Health Bureau (2014-2-003)

Abstract:

Uveal melanoma is a most common intraocular malignant tumor in adults. Though rates of uveal melanoma local control is high, as many as half of patients can develop hematogenous metastases. Some clinical and histopathologic factors, genetic characteristics are associated with an increased risk of metastasis. Early detection of these characteristics is helpful for evaluating prognosis, choicing individualized treatment strategy and prolonging survival time. (Int Rev Ophthalmol, 2016, 40: 306-309)